The effects of magnesium supplementation on sensorineural hearing damage: A critical review of the literature

This critical review examines the effects of magnesium supplementation on auditory damage associated with noise-induced and idiopathic sudden sensorineural hearing loss. Study designs included three randomized, placebo-controlled trial experiments and one crossover experiment. Overall, evidence suggests that there is potential for magnesium supplementation as a treatment for noise-induced and idiopathic sudden sensorineural hearing loss in adults. It is recommended that additional studies be completed with larger and more diverse subject populations and with proper controls to account for the effects of presbycusis, noiseexposure, auditory disease, and individual magnesium levels. It is also recommended that additional studies be completed to determine proper dose response curves and best means of magnesium administration.